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Graham Little-Piccardi-Lassueur syndrome
1 associated gene
7 signs/symptoms
PROTEIN INTERACTIONS: 1
Narcolepsy without cataplexy
3 associated genes
4 signs/symptoms
Graham Little-Piccardi-Lassueur syndrome
Narcolepsy without cataplexy

HLA-DRA
(UniProt - OMIM)
 HCRT
(UniProt - OMIM)
HLA-DQB1
(UniProt - OMIM)
HLA-DRB1
(UniProt - OMIM)

INTERACTOME
ASSOCIATIONS
(click on a score value to see the evidence)
HLA-DRA
(0.88)
HLA-DRB1


Citations in the biomedical literature:


Graham Little-Piccardi-Lassueur syndrome
HLA-DRA
Narcolepsy without cataplexy
HCRT HLA-DQB1 HLA-DRB1



Graham Little-Piccardi-Lassueur syndrome
Narcolepsy without cataplexy

Synonym(s):
- Graham Little syndrome
- Piccardi-Lassueur-Little syndrome
Synonym(s):
(no synonyms)
Classification (Orphanet):
- Rare genetic disease
- Rare skin disease
Classification (Orphanet):
- Rare neurologic disease
Classification (ICD10):
- Diseases of the skin and subcutaneous tissue -
Classification (ICD10):
- Diseases of the nervous system -
Epidemiological data:
(no data available)
Epidemiological data:
Class of prevalence: unknown
Average age onset: adolescence / young
Average age of death: normal
Type of inheritance: unknown
External references:
No OMIM references
No MeSH references
External references:
No OMIM references
No MeSH references
Graham Little-Piccardi-Lassueur syndrome
Narcolepsy without cataplexy

Very frequent
- Alopecia
- Decreased body hair / axillar / pubic hairlessness
- Follicular / erythematous / edematous papules / milium
- Hyperkeratosis / ainhum / hyperkeratotic skin fissures
- Hypotrichosis / atrichia / atrichiasis / scalp hairlessness

Frequent
- Lichen
- Pruritus / itching



Very frequent
- Delirium / hallucination
- Sleep and vigilance disorders
- Somnolence / hypersomnia / parasomnia

Occasional
- Psychic / behavioural troubles